4,5-Dihydropyrrolo[1,2-a]quinoxalines: A Tunable and Regenerable Biomimetic Hydrogen Source

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4,5-Dihydropyrrolo[1,2-a]quinoxalines: a tunable and regenerable biomimetic hydrogen source.

A series of tunable and regenerable biomimetic hydrogen sources, 4,5-dihydropyrrolo[1,2-a]quinoxalines, have been synthesized and applied in biomimetic asymmetric hydrogenation of 3-aryl-2H-benzo[b][1,4]oxazines and 1-alkyl-3-aryl-quinoxalin-2(1H)-ones, providing the chiral amines with up to 92% and 89% ee, respectively.

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ژورنال

عنوان ژورنال: Organic Letters

سال: 2014

ISSN: 1523-7060,1523-7052

DOI: 10.1021/ol500176v